Factors predictive of insulin resistance syndrome in Hispanic children

Date of Award




Degree Name

Doctor of Philosophy (Ph.D.)


Clinical Psychology

First Committee Member

Alan M. Delamater - Committee Chair


The present study was conducted to promote a greater understanding of the development of IRS and to determine which children are at greatest risk. This study incorporates a prospective design to investigate the risk factors responsible for the development of symptoms of adult chronic disease in childhood, focusing on the insulin resistance syndrome (IRS) as the outcome variable. The interrelationship or clustering of IRS risk factors themselves and the relationships among body mass, physical activity, diet, and risk factors has yet to be studied with young Hispanic children. In addition, the potential moderating influence of family history of health risks and mediating influence of physical activity and dietary intake are examined to determine which variables may account for the expression of IRS.Forty seven children were recruited from three area elementary schools. Laboratory analyses, anthropometric data, and measures of physical activity and dietary intake are included. Results reveal the relationships among IRS, its components, and the body mass index (BMI). Mediator analyses conducted with physical activity and dietary intake reveal no significant influence on the relationship between zBMI and IRS. Family history of type 2 diabetes does not moderate the relationship between zBMI and IRS.Implications for understanding the development of IRS in young Hispanic children are discussed. The role of obesity and BMI is highlighted. Prevention and intervention strategies also are discussed.


Health Sciences, Public Health; Psychology, Clinical; Psychology, Physiological

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Link to Full Text