Aerobic exercise training and the immune system
Date of Award
Doctor of Philosophy (Ph.D.)
First Committee Member
Neil Schneiderman, Committee Chair
Healthy gay males (n = 14) at high risk for AIDS, whose human immunodeficiency virus antibody status was negative, were randomly assigned to control (n = 7) or aerobic exercise training (n = 7) groups. The exercisers received 45 min of aerobic training, at an intensity of 70-80% predicted maximum heart rate, 3 times per week. After 10 weeks, a significant 8.5% increase in fitness level was obtained for the exercisers as measured by VO2max. The control group showed no significant changes in fitness level across a similar 10 week period. Aerobic exercise training produced a significant increase in the number of T4-helper cells, 2H4+T4+ subset of T4 cells, and B1 cells. In contrast, subjects in the control group did not show significant changes in T4 cells, 2H4+T4+, or B1 cells. These data collectively provide evidence that an aerobic exercise training program may enhance both cellular and humoral immunity.
Health Sciences, Immunology
Laperriere, Arthur R., "Aerobic exercise training and the immune system" (1988). Dissertations from ProQuest. 2680.