Publication Date



Open access

Degree Type


Degree Name

Doctor of Education (EDD)


Kinesiology and Sport Sciences (Education)

Date of Defense


First Committee Member

Kevin A. Jacobs

Second Committee Member

Joseph F. Signorile

Third Committee Member

Arlette C. Perry

Fourth Committee Member

Armando Mendez


Regular aerobic exercise may reduce cardiovascular disease (CVD) risk in part by lowering the concentration of inflammatory markers such as C-reactive protein (CRP). While studies in diseased populations have shown significant decreases in CRP concentrations with regular aerobic training, little has been conclusively determined regarding the effects of aerobic training on CRP concentrations in apparently healthy, untrained populations who may not be adequately screened for CVD risk by traditional methods. PURPOSE: To examine the effects of a 17-wk half marathon training program (TP) on CRP concentrations, aerobic fitness, and body composition in apparently healthy, untrained men. METHODS: Twenty men (29.3 ± 1.0 yr, 37.0 ± 1.6 mL•kg-1•min-1 VO2max, 29.1 ± 1.8% body fat) registered as training subjects (TRN) in a 17-wk half marathon TP. An additional 22 men (27.8 ± 1.4 yr, 38.8 ± 1.0 mL•kg-1•min-1 VO2max, 26.8 ± 1.4% BF) served as controls (CON). Fasting blood samples were taken at four time points over the TP and were analyzed for CRP and interleukin-6 (IL-6) concentrations. Aerobic capacity (VO2max) and body fat (BF%) were measured before and after the TP. RESULTS: No significant changes in CRP (P=0.69) or IL-6 concentrations (P=0.73) were seen in TRN as a result of the TP despite significant improvements in VO2max (42.2 ± 1.9 ml•kg-1•min-1, P


BMI; Cardiovascular Disease Risk; Body Fat; Inflammation; Aerobic Fitness