Publication Date

2018-07-03

Availability

Embargoed

Embargo Period

2019-07-03

Degree Type

Dissertation

Degree Name

Doctor of Philosophy (PHD)

Department

Biomedical Engineering (Engineering)

Date of Defense

2018-06-21

First Committee Member

Herman S. Cheung

Second Committee Member

Matthias A. Salathe

Third Committee Member

C.Y. Charles Huang

Fourth Committee Member

Edward A. Dauer

Fifth Committee Member

Daniel Pelaez

Abstract

The electronic cigarette (EC) has recently been deemed as a “safer alternative” to cigarette smoking; however, EC are still believed to cause major health concerns due to the concentrated delivery of toxic chemicals. ECs have not been fully regulated by the FDA and the long-term effects of EC vapor exposure have yet to be identified, yet according to the 2016 Surgeon General Report, EC use among young adults has grown by more than 900% within the last 5 years and is currently the most popular form of tobacco use among this group. The proposed research will investigate how EC use and differences in EC e-liquid components affect dental stem cell health in order to determine the extent of biological changes and the ultimate long-term consequences of EC use on oral health.

Keywords

Stem Cells; Periodontal Ligament Derived Stem Cells; Electronic Cigarette; Nicotine; E-liquid; Cigarette Smoking

Available for download on Wednesday, July 03, 2019

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