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Doctor of Philosophy (PHD)
Biochemistry and Molecular Biology (Medicine)
Date of Defense
First Committee Member
Second Committee Member
Sapna K. Deo
Third Committee Member
The development of technology that can be used to quickly and reliably assay a wide variety of matrices for the presence of specific small molecules has long been a high priority for scientists. These methods are valuable tools that see use in many fields, including biomedicine and environmental analysis. Although many contemporary technologies exist, their use is, for the most part, limited by their expense, required instrumentation, and long assay times. In an effort to address these limitations, many examples of biotechnology have been produced and this interest in biosensors continues. Herein, a number of projects to develop new bioanalytical techniques and refine existing methods are detailed and the use of these biosensing platforms is validated using both prepared samples and samples collected from the field.
whole cell biosensor; environmental pollution; small molecule detection; bacteria; paper-based analytical systems
Wynn, Daniel, "The Detection of Hazardous Materials Using Genetically Engineered Bacteria" (2018). Open Access Dissertations. 2236.
Available for download on Sunday, May 31, 2020