Publication Date



Open access

Degree Type


Degree Name

Doctor of Philosophy (PHD)


Kinesiology and Sport Sciences (Education)

Date of Defense


First Committee Member

Joseph F. Signorile

Second Committee Member

Sheah L. Rarback

Third Committee Member

Warren Whisenant

Fourth Committee Member

Arlette C. Perry


The purpose of the present study was to test the acute effects of a dietary supplement, having as its major ingredient an extract of ginseng, on grip strength, lower body power output, cardiovascular markers, metabolic markers, hormones, and mood state. Twelve experienced resistance-trained men (28.3 ± 5.7 yrs) were randomly administered placebo (P), single dose (SD) and double dose (DD) of the supplement on separate days. Diet and activity levels were kept constant across testing days. On each day, subjects began with the Profile of Mood States (POMSpre1), blood draws (BDpre1), blood pressure (BPpre1), and heart rate (HRpre1) assessments, then ingested the drink and sat quietly for 30 minutes. BDpre2, BPpre2, and HR pre1 were then taken. Subjects performed the grip strength and cycle ergometer tests followed immediately by BDpost, HRpost, and BPpost and POMSpost. The testing session ended with blood draws, heart rates, and blood pressures being taken 30 (post30), 60 (post60), 120 (post120) and 180 (post180) minutes post exercise. Grip strength did not differ between P, SD, or DD treatments. Cycle ergometry peak power (PP), average power (AP) and total work (TW) were significantly higher for the SD and DD than P; however, no significant difference existed between SD and DD treatments. For LH and T significant differences were found among all treatment conditions. There were no significant treatment effects for HR, BP, glucose, insulin, lactate, GH or PRL or for the POMS. There was a significant treatment*time interaction for ACTH (p < .05). Post hoc analysis indicated that at Tpost ACTH was significantly lower for D treatment vs P or S treatments (p < .05) and at Tpost60 ACTH was significantly lower for S and D treatments vs P treatment (p < .05). There was significant differences in C between the D treatment (260.45 ± 15.58 nmol•L-1) and the P (336.08 ± 27.59 nmol•L-1) and S (311.14 ± 21.01 nmol•L-1) treatments (p < .001). There was a significant difference for T:C ratio values among P (0.0810 ± 0.0090), S (0.0960 ± 0.0130) and D (0.1410 ± 0.0190) treatments (p < .001). Acute ingestion of a polynutrient supplement containing a standardized ginseng tract, was able to increase PP, AP, TW LH, and testosterone and decrease ACTH and cortisol. No significant effects were found for GH, PRL, insulin, glucose, lactate, HR, BP or POMS scores. Acute ingestion of a polynutrient supplement was able to increase performance and the anabolic environment in resistance trained men.


Testosterone; Cortisol; Adrenocorticotropic Hormone; Panax Ginseng; Luteinizing Hormone