Off-campus University of Miami users: To download campus access dissertations, please use the following link to log into our proxy server with your University of Miami CaneID and Password.

Non-University of Miami users: Please talk to your librarian about requesting this dissertation through interlibrary loan.

Publication Date



UM campus only

Embargo Period


Degree Type


Degree Name

Doctor of Philosophy (PHD)


Chemistry (Arts and Sciences)

Date of Defense


First Committee Member

Angel E. Kaifer

Second Committee Member

Burjor Captain

Third Committee Member

Rajeev Prabhakar

Fourth Committee Member

Adam R. Urbach


This dissertation mainly investigate the host-guest chemistry in different supramolecular systems using nitroxide as spin probes. Two topics in supramolecular chemistry are involved in this dissertation: (a) self-assembled hexameric molecular capsules and (b) cucurbituril complexes. In addition to this, the author also describes a new M4L6 tetrahedral metal-organic cage formed by sulfate-templated self-assembly. The first chapter in this dissertation gives a brief introduction to supramolecular chemistry. The second chapter describes the EPR and NMR investigation on the interactions of nitroxide probes with resorcin[4]arene molecular capsules. Four chapters of this dissertation deal with the complexation behavior of cucurbit[n]urils (n = 7,8) with different ferrocene and cobaltocenium nitroxide derivatives. The last chapter describes the preparation and characterization of a M4L6 tetrahedral molecular cage formed by both sulfate-templated and subcomponent self-assembly.


Supramolecular Chemistry; EPR; Nitroxide; Spin Probes; Cucurbituril; Self-Assembly